Backcross Project
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We have recently become involved in a project to help with the problem of high uric acid in all Dalmatians. Because of the high uric acid many Dalmatians form urate stones. That condition can cause them to block and it can become life threatening. The following article explains about the beginnings of that project. The project is referred to as the backcross project. There are many breeders that are now trying to produce Normal Uric Acid Dalmatians.
The “Dalmatian Backcross Project” commenced in 1973 with the original outcross
of an AKC registered Champion Pointer sire bred to an AKC registered Dalmatian dam.
Dr. Robert Schaible conducted the breeding in an effort to address the fixed genetic defect in Dalmatians that affects uric acid metabolism and that may lead to increased urinary uric acid, urate crystals,
urinary bladder aggregate formation, stones, urinary tract obstruction and even death.
This wonderful breeding program is presently at the 14th generation from the original cross.
The progeny have 99.98% AKC registered Dalmatians in their pedigrees and on parentage analysis,
their DNA is 99.8% the same as AKC registered Dalmatians.
Normal Uric Acid dogs (NUA) <also referred to as Low Uric Acid (LUA)> exhibit a 10-fold lower urinary uric acid to creatinine ratio when compared to other Dalmatians with high Uric Acid (HUA).
of an AKC registered Champion Pointer sire bred to an AKC registered Dalmatian dam.
Dr. Robert Schaible conducted the breeding in an effort to address the fixed genetic defect in Dalmatians that affects uric acid metabolism and that may lead to increased urinary uric acid, urate crystals,
urinary bladder aggregate formation, stones, urinary tract obstruction and even death.
This wonderful breeding program is presently at the 14th generation from the original cross.
The progeny have 99.98% AKC registered Dalmatians in their pedigrees and on parentage analysis,
their DNA is 99.8% the same as AKC registered Dalmatians.
Normal Uric Acid dogs (NUA) <also referred to as Low Uric Acid (LUA)> exhibit a 10-
